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Biao Xu Selected Research

phenylalanyl- leucyl- phenylalanyl- glutaminyl- prolyl- glutaminyl- arginyl- phenylalaninamide

8/2020Spinal administration of the multi-functional opioid/neuropeptide FF agonist BN-9 produced potent antinociception without development of tolerance and opioid-induced hyperalgesia.
1/2020Central and peripheral modulation of gastrointestinal transit in mice by DN-9, a multifunctional opioid/NPFF receptor agonist.
1/2019Discovery of two novel branched peptidomimetics containing endomorphin-2 and RF9 pharmacophores: Synthesis and neuropharmacological evaluation.
12/2018Analgesic activities of the mixed opioid and NPFF receptors agonist DN-9 in a mouse model of formalin-induced orofacial inflammatory pain.
10/2017Peripheral and central sites of action for anti-allodynic activity induced by the bifunctional opioid/NPFF receptors agonist BN-9 in inflammatory pain model.

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Biao Xu Research Topics

Disease

36Myocardial Infarction
08/2022 - 01/2005
22Fibrosis (Cirrhosis)
08/2022 - 12/2003
21Heart Failure
08/2022 - 01/2011
20Inflammation (Inflammations)
08/2022 - 08/2012
20Neoplasms (Cancer)
08/2022 - 09/2007
17Tuberculosis (Tuberculoses)
01/2021 - 11/2009
16Pain (Aches)
02/2022 - 11/2016
14Ischemia
10/2020 - 01/2005
13Atrial Fibrillation
08/2022 - 01/2015
12Infarction (Infarctions)
01/2022 - 04/2009
12Atherosclerosis
01/2022 - 03/2017
12Infections
11/2021 - 04/2006
10Cardiovascular Diseases (Cardiovascular Disease)
10/2022 - 01/2012
10Thrombosis (Thrombus)
01/2019 - 10/2007
9Hypertension (High Blood Pressure)
08/2022 - 01/2007
9Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis)
01/2022 - 06/2008
7ST Elevation Myocardial Infarction
06/2021 - 07/2016
7Type 2 Diabetes Mellitus (MODY)
01/2021 - 10/2005
6Stroke (Strokes)
01/2022 - 04/2010
6Acute Kidney Injury (Acute Renal Failure)
01/2022 - 01/2015
6Hyperalgesia
01/2022 - 10/2017
5Death (Near-Death Experience)
02/2022 - 01/2014
5Hemorrhage
01/2022 - 01/2016
5Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2022 - 01/2012
5Hypoxia (Hypoxemia)
01/2021 - 10/2009
5Hypertrophy
08/2020 - 06/2013
5Myocardial Ischemia (Ischemic Heart Diseases)
01/2020 - 01/2005
4Obesity
01/2022 - 04/2010
4Constipation
01/2021 - 10/2018
4Neuralgia (Stump Neuralgia)
01/2021 - 10/2018
4Breast Neoplasms (Breast Cancer)
11/2020 - 01/2008
4Postoperative Pain
08/2020 - 01/2018
4Diabetes Mellitus
05/2018 - 01/2016
4Coronary Artery Disease (Coronary Atherosclerosis)
11/2017 - 11/2012
3Cardiotoxicity
04/2022 - 01/2020
3Metabolic Diseases (Metabolic Disease)
01/2022 - 09/2015
3Intrahepatic Cholestasis of Pregnancy
01/2022 - 08/2016
3Hepatitis B
11/2021 - 07/2017
3Chronic Renal Insufficiency
10/2021 - 05/2016
3Visceral Pain
08/2020 - 01/2018
3Extensively Drug-Resistant Tuberculosis
07/2020 - 08/2013
3Wounds and Injuries (Trauma)
11/2019 - 12/2007

Drug/Important Bio-Agent (IBA)

22Pharmaceutical PreparationsIBA
01/2022 - 12/2007
13Proteins (Proteins, Gene)FDA Link
02/2022 - 04/2009
12Analgesics (Analgesic Drugs)IBA
01/2022 - 12/2007
10Doxorubicin (Adriamycin)FDA LinkGeneric
04/2022 - 01/2012
10Opioid Analgesics (Opioids)IBA
07/2021 - 10/2017
10CollagenIBA
10/2020 - 04/2006
9Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2008
9CytokinesIBA
01/2022 - 06/2006
8Glucose (Dextrose)FDA LinkGeneric
01/2022 - 08/2016
8integrin-linked kinaseIBA
05/2017 - 09/2009
7Formaldehyde (Formol)FDA Link
02/2022 - 11/2016
7Syndecan-4IBA
01/2022 - 08/2012
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2012 - 04/2006
6omega-Chloroacetophenone (Mace)IBA
02/2022 - 01/2014
5Triglycerides (Triacylglycerol)IBA
01/2022 - 12/2019
5Bile Acids and Salts (Bile Acids)IBA
01/2022 - 08/2016
5MicroRNAs (MicroRNA)IBA
01/2021 - 01/2012
5Therapeutic UsesIBA
12/2020 - 04/2006
5phenylalanyl- leucyl- phenylalanyl- glutaminyl- prolyl- glutaminyl- arginyl- phenylalaninamideIBA
08/2020 - 10/2017
5Opioid Receptors (Opioid Receptor)IBA
08/2020 - 06/2017
4empagliflozinIBA
01/2022 - 01/2021
4Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2021 - 01/2011
4LipidsIBA
01/2021 - 09/2018
4CholesterolIBA
01/2021 - 12/2020
4neuropeptide FF receptorIBA
08/2020 - 10/2017
4CarrageenanIBA
03/2020 - 10/2017
4Peptides (Polypeptides)IBA
01/2020 - 06/2017
4Folic Acid (Vitamin M)FDA LinkGeneric
11/2016 - 01/2008
3ColchicineFDA LinkGeneric
08/2022 - 01/2021
3SaltsIBA
08/2022 - 02/2007
3Narcotic Antagonists (Opioid Antagonists)IBA
02/2022 - 10/2017
3p38 Mitogen-Activated Protein KinasesIBA
01/2022 - 11/2018
3InflammasomesIBA
01/2022 - 01/2016
3Sodium-Glucose Transporter 2 InhibitorsIBA
01/2022 - 01/2018
3Angiotensin IIIBA
12/2021 - 01/2016
3Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
07/2021 - 01/2012
3Indicators and Reagents (Reagents)IBA
07/2021 - 05/2015
3Reactive Oxygen Species (Oxygen Radicals)IBA
07/2021 - 07/2018
3mu Opioid Receptors (mu Opioid Receptor)IBA
07/2021 - 11/2018
3Sodium-Glucose Transport ProteinsIBA
06/2021 - 01/2018
3Acetic Acid (Vinegar)FDA LinkGeneric
08/2020 - 01/2018
3Blood Glucose (Blood Sugar)IBA
01/2020 - 08/2008
3CannabinoidsIBA
01/2020 - 06/2017
3Rifampin (Rifampicin)FDA LinkGeneric
11/2019 - 11/2009
3Anti-Bacterial Agents (Antibiotics)IBA
11/2019 - 12/2007
3DNA (Deoxyribonucleic Acid)IBA
01/2019 - 08/2009
3Naloxone (Narcan)FDA LinkGeneric
01/2019 - 10/2017
3Messenger RNA (mRNA)IBA
11/2018 - 04/2006

Therapy/Procedure

21Therapeutics
02/2022 - 04/2010
10Percutaneous Coronary Intervention
06/2021 - 06/2016
8Transplantation
04/2022 - 05/2013
8Analgesia
03/2020 - 06/2017
8Stents
12/2018 - 01/2014
6Patient Readmission
01/2022 - 08/2016
5Ligation
12/2014 - 01/2005
4Spinal Injections
01/2022 - 11/2018
3Drug Therapy (Chemotherapy)
01/2022 - 06/2008
3Drug-Eluting Stents
01/2020 - 01/2017